Natura Inside Premium Cannabis Oil – 7% CBD with Piperine & Coffee Oil, Dryas Series, 10ml

CBD Coffee Drops with Piperine
Natural Synergy for Daily Premium Care

Dryas is crafted with CBD, cold-pressed Arabica coffee seed oil, and piperine, offering a plant-based formulation that can be easily integrated into daily routines. The blend combines full extract CBD with natural oils, designed to support a balanced lifestyle.

Features

• CBD Content: 7% (700mg per 10ml)

• With Piperine: Included to support ingredient bioavailability

• Cold-Pressed Coffee Seed Oil: Adds a natural touch from Arabica coffee seeds

• Plant-Based: Made with carefully selected natural ingredients

🧪 How to Use
• Shake well before use
• Apply a small amount 2–3 times daily, preferably every day
• Store in a cool, dark place at room temperature (15–25 °C)

Want to learn more about cannabidiol & coffee oil? Check out this short blog.

🧬 Cannabidiol (CBD) and Scientifically Documented Properties

Cannabidiol (CBD) is a natural phytocannabinoid derived from the Cannabis sativa plant. Unlike tetrahydrocannabinol (THC), CBD is non-psychoactive, making it safe for daily use¹. It interacts with the endocannabinoid system (ECS), which regulates key physiological functions such as anxiety, pain, sleep, and immune balance².

📌 Key Properties Identified in Scientific Literature:
• Anxiety and stress relief: CBD appears to interact with serotonin receptors, contributing to anxiolytic effects³. It has been studied in cases of social anxiety, generalized anxiety disorder, and PTSD.
• Sleep support: Research shows that CBD may improve sleep quality and duration, particularly when sleep disturbances are related to anxiety⁴.
• Anti-inflammatory and analgesic properties: CBD influences CB1, CB2, and TRPV1 receptors, supporting relief from chronic or neuropathic pain and reducing inflammation⁵.
• Physiological balance (homeostasis): By modulating the ECS, CBD may help support general wellbeing and internal balance⁶.
• Antioxidant and immunomodulatory effects: Experimental data suggest CBD may reduce pro-inflammatory cytokines and support immune response⁷.

References

1. World Health Organization. (2018). Cannabidiol (CBD) Critical Review Report.

2. Lowe, H. I. C., Toyang, N. J., & McLaughlin, W. (2021). Medicines, 8(6), 44. https://doi.org/10.3390/medicines8060044

3. Blessing, E. M., et al. (2015). Neurotherapeutics, 12(4), 825–836. https://doi.org/10.1007/s13311-015-0387-1

4. Shannon, S., et al. (2019). The Permanente Journal, 23. https://doi.org/10.7812/TPP/18-041

5. Whiting, P. F., et al. (2015). JAMA, 313(24), 2456–2473. https://doi.org/10.1001/jama.2015.6358

6. Nichols, J. M., & Kaplan, B. L. (2020). Cannabis and Cannabinoid Research, 5(1), 12–31. https://doi.org/10.1089/can.2018.0073

7. Kozela, E., et al. (2011). Journal of Neuroimmune Pharmacology, 6(3), 529–540. https://doi.org/10.1111/j.1476-5381.2011.01379.x

8. Stahl, V., & Vasudevan, K. (2020). Cureus, 12(1), e6809. https://doi.org/10.7759/cureus.6809

9. Iffland, K., & Grotenhermen, F. (2017). Cannabis and Cannabinoid Research, 2(1), 139–154. https://doi.org/10.1089/can.2016.0034

10. Regulation (EU) No 1307/2013 and Directive 2002/46/EC – EU compliance on hemp and novel foods

☕ Coffee Oil: A Multifunctional Bioactive for Skin Health and Inner Balance

Coffee oil, obtained through the cold pressing of green or roasted coffee beans, is a bioactive-rich extract containing diterpenes (cafestol, kahweol), tocopherols (vitamin E), phytosterols, and polyphenols. These compounds offer dual benefits for both topical (skin care) and systemic (nutritional) applications. When used on the skin, coffee oil exhibits antioxidant, anti-inflammatory, and revitalizing properties—helping to protect against oxidative stress, improve elasticity, and support the skin barrier. Its essential fatty acids contribute to hydration and smoothness, while caffeine and diterpenes help stimulate microcirculation, enhancing skin tone and radiance (Dourado et al., 2020; Herman & Herman, 2013).

When taken as a supplement, the same bioactive molecules act internally to protect cells from oxidative damage, support liver detoxification, and promote lipid balance. Diterpenes such as cafestol and kahweol activate phase II detoxifying enzymes and glutathione synthesis, reinforcing liver function (Cavin et al., 2002). Meanwhile, phytosterols like β-sitosterol and stigmasterol assist in cholesterol regulation and cardiovascular support (Godos et al., 2014). Overall, coffee oil represents a synergistic botanical ingredient that supports skin vitality, cellular protection, and systemic well-being, bridging the connection between outer beauty and inner health.

References:

• Cavin, C., Holzhaeuser, D., Scharf, G., Constable, A., Huber, W. W., & Schilter, B. (2002). Cafestol and kahweol, two coffee-specific diterpenes with anticarcinogenic activity. Food and Chemical Toxicology, 40(8), 1155–1163.

• Dourado, G. K. Z. S., de Souza, A. L. R., & dos Santos, P. O. (2020). Coffee oil as an ingredient in cosmetics: A review. Journal of Cosmetic Dermatology, 19(9), 2407–2414.

• Godos, J., Pluchinotta, F. R., Marventano, S., Buscemi, S., Li Volti, G., Galvano, F., & Grosso, G. (2014). Coffee components and cardiovascular risk: Beneficial and detrimental effects. Public Health Nutrition, 17(9), 2073–2089.

• Herman, A., & Herman, A. P. (2013). Caffeine’s mechanisms of action and its cosmetic use. Skin Pharmacology and Physiology, 26(1), 8–14.

Note: This product is registered in the European CPNP database with Notification Number: CPNP 4619441.

The information presented is based on published scientific literature regarding the compounds and does not constitute a health claim for the final product. This product is not intended to diagnose, treat, cure, or prevent any disease.